Number 2 Royal Terrace was the third house in the terrace, located towards the eastern end of the block, overlooking the River Thames.
The first resident of this house is not known. There is an extant lease for an unknown house on the Royal Terrace, possibly for this house. It was signed by John Blake (unknown) on 2 August 1774, with a purchase price of £2,700, and a ground rent of £34/13/0 per annum. In 1870-74 the National Cottage Hospital for Consumption was resident; and in 1880-1907 the London Bible Mission and the Indian Female Normal School Society had their offices here.