The yellow taffeta bedchamber is located on the bedroom storey of the house, in the north range, and adjacent to the great staircase to the east.

This is one of very few rooms worked on by Adam for which he designed furniture, but was otherwise uninvolved in the interior decoration. This happened elsewhere at Osterley, in the gallery, and the breakfast room.

The bed for the yellow taffeta bedchamber was executed in gilt wood and satinwood in accordance with Adam's design, and lined with white silk. It survives in situ. A pier glass and a frame for a Chinese painting on glass (now in the breakfast room) were also designed for this room, and both can be attributed to Adam on stylistic grounds, although there are no extant drawings.